We are working on design and synthesis of chelate compounds and nanoparticles for biomedical applications. MRI contrast agents, in vitro diagnosis, drug delivery, cancer diagnosis and treatment, and nano-bio interactions are our research subjects.

林泓域
副教授
电话:86-592-2181963
办公室:卢嘉锡楼542室
电子邮箱:hylin007(AT)xmu.edu.cn

个人简历:

南京大学化学化工学院 理学学士(2003-2007)

美国Brandeis University化学系 理学博士(2007-2012)

Brandeis University Career Development Fellowship (2007-2012)

美国Cornell University化学与化学生物学系 博士后(2013-2015)

厦门大学化学化工学院化学生物学系 副教授(2016- )

研究兴趣:

分子磁共振造影剂

分子诊疗试剂

分子探针

近期主要代表论著:

1. Lirong Wang; Hongyu Lin; Xiaoqin Chi; Chengjie Sun; Jiaqi Huang; Xiaoxue Tang; Hongming Chen; Xiangjie Luo; Zhenyu Yin; and Jinhao Gao*A Self‐Assembled Biocompatible Nanoplatform for Multimodal MR/Fluorescence Imaging Assisted Photothermal Therapy and Prognosis Analysis. Small 2018, 14, 1801612.

2. Lirong Wang; Hongyu Lin; Lingceng Ma; Jianbin Jin; Taipeng Shen; Ruixue Wei; Xiaomin Wang; Hua Ai; Zhong Chen; and  Jinhao Gao* Self‐Assembled Biocompatible Nanoplatform for Multimodal MR/Fluorescence Imaging Assisted Photothermal Therapy and Prognosis Analysis. Nanoscale 2017, 9, 4516-4523.

3. Xianglong Zhu; Hongyu Lin; Lirong Wang; Xiaoxue Tang; Lengceng Ma; Zhong Chen; and Jinhao Gao* Surface and Interfacial Engineering of Iron Oxide Nanoplates for Highly Efficient Magnetic Resonance Angiography. ACS Appl. Mater. Interfaces, 2017, 9 , 21688–21696.

4. Lirong Wang;  Hongyu Lin;  Lengceng Ma; Chengjie Sun; Jiaqi Huang;  Ao Li; Tian Zhao; Zhong Chen; and Jinhao Gao* Geometrical confinement directed albumin-based nanoprobes as enhanced T1 contrast agents for tumor imaging. J. Mater. Chem.B 2017, 5, 8004-8012.

5. Lin, H.-Y.; Haegele, J. A.; Disare, M. T.; Lin, Q.; Aye, Y. “A Generalizable Platform for Interrogating Target- and Signal-Specific Consequences of Electrophilic Modifications in Redox-Dependent Cell Signaling” J. Am. Chem. Soc. 2015, 137, 6232-6244.

6. Parvez, S.; Fu, Y.; Li, J.; Long, M. J. C.;Lin, H.-Y.; Lee, D. K.; Hu, G.S.; Aye, Y. “Substoichiometric Hydroxynonenylation of a Single Protein Recapitulates Whole-Cell-Stimulated Antioxidant Response” J. Am. Chem. Soc. 2015, 137, 10-13.

7. Fu, Y.; Lin, H.-Y.; Wisitpitthaya, S.; Blessing, W. A.; Aye, Y. “A fluorimetric Readout Reporting the Kinetics of Nucleotide-induced Human Ribonucleotide Reductase Oligomerization” ChemBioChem 2014, 15, 2598-2604.

8. Lin, H.-Y.; Snider, B. B. “Mn(OAc)3-Based a'-Oxidative Acetoxylation of N-Trifluoroacetyl Vinylogous Amides” Heterocycles 2012, 86, 1391-1400. (作为邀稿发表于Heterocycles第86卷根岸英一教授(Prof. Ei-ichi Negishi,2010年诺贝尔化学奖得主)77岁生日纪念特刊上。)

9. Lin, H.-Y.; Causey, R.; Garcia, G. E.; Snider, B. B. “Synthesis of (±)-7-Hydroxylycopodine” J. Org. Chem. 2012, 77, 7143-7156. (这篇文章被选为Featured Article 以及2012年第17期封面文章,是2012年该期刊被阅读次数最多的文章之一。)

10. Lin, H.-Y.; Snider, B. B. “Synthesis of Phidianidines A and B” J. Org. Chem. 2012, 77, 4832-4836.

11. Lin, H.-Y.; Snider, B. B. “Synthesis of (±)-7-Hydroxylycopodine” Org. Lett. 2011, 13, 1234-1237.。

12. Pan, H.;Lin, H.; Shen Q.; Zhu J.-J. “Cadmium(II) (8-Hydroxyquinoline) Chloride Nanowires: Synthesis, Characterization and Glucose-Sensing Application” Adv. Funct. Mater. 2008, 18, 3692-3698.